Asthma diagnosis and treatment – 1022. The differences of clinical profiles by house dust mite sensitzation in patients with asthmatics in Soonchunhyang University Hospital cohort
نویسندگان
چکیده
Results HDM sensitization rate was higher prevalence in male than in female. Compared with non-HDM sensitization asthmatics, HDM positive asthmatics had early onset of age (D. farina, 39.0 ± 0.50 vs. 48.5 ± 0.42, p=0.001; D. pteronyssinus, 39.4 ± 0.50 vs. 48.3 ± 0.43, p=0.001). HDM positive asthmatics had shorter duration of asthma symptom than that of HDM negative asthmatics. HDM negative asthmatics had lower FEV1/FVC % than those of HDM positive asthmatics. PC20 in HDM positive asthmatics had lower than those of HDM negative asthmatics (D. farina, 5.59 ± 0.25 mg/ml vs. 6.82 ± 0.28 mg/ml, p=0.001; D. pteronyssinus, 5.54 ± 0.24 mg/ml vs. 6.87 ± 0.28 mg/ml, p=0.001). Blood eosinophils number in D. pteronyssinus positive asthmatics had higher than that of D. pteronyssinus negative asthmatics (400.7 ± 12.5 vs. 373.5 ± 15.3, p<0.05). Total IgE in HDM positive asthmatics had higher than that of HDM negative asthmatics. There was no difference of BMI between two groups.
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